Technical Specifications

The DUSA Shaker DTS 100i is a semi-automation solution from Copley Scientific for delivered dose uniformity (DDU) testing of metered dose inhalers (MDIs) and dry powder inhalers (DPIs). It automates the internal rinsing of Dose Uniformity Sampling Apparatus collection tubes, a step that is otherwise manual, prone to operator variability, and carries a risk of repetitive strain injury . The unit offers a choice of shaking, rolling, or combined motion, with programmable speed and duration. The specifications below cover the standard unit.

Model/Part Number: DTS 100i

Capacity and Rinsing Action

• Capacity: 10 DUSA tubes for MDIs; 10 DUSA tubes for DPIs

• Rinsing action options: Shake only, Roll only, Shake and Roll

• Shake speed range: 20–200 RPM

• Roller speed: Fixed at 11.4 RPM

• Run time: Up to 100 hours

User Interface and Connectivity

• User interface: Touchscreen

• Connectivity: USB A, USB B, RS-232

Physical Specifications

• Dimensions (W x D x H): 410 x 626 x 227 mm

Standard Accessories Included:

• DTS 100i base unit

• Power cable

• Operating manual

Items Excluded:

• DUSA collection tubes (MDI or DPI)

• IQ/OQ documentation (available as a separate option)

• Calibration certificates

• Additional fixtures for non-standard tube geometries

Pre-installation Requirement:
Place the DTS 100i on a level bench with clearance for the 410 x 626 mm footprint and access to the touchscreen. Connect to a grounded power supply matching the nameplate. Fit the appropriate DUSA tube holders before the first run. Confirm the shaking and rolling mechanisms move freely through their full range before loading samples.

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Why This System Belongs in an Inhaler Testing Lab

Delivered dose uniformity testing is mandatory for every inhaled product, and the step that most often compromises the result is the one done by hand: rinsing the drug out of the DUSA collection tube. Manual agitation is prone to inter- and intra-operator variability, and any failure to wet all internal walls compromises recovery and the integrity of the data .

The DUSA Shaker DTS 100i automated dose recovery system standardises that step. It holds up to ten MDI or DPI collection tubes and subjects them to a controlled shaking and/or rolling action, with the shake speed adjustable from 20 to 200 RPM and the roller speed fixed at 11.4 RPM . The same motion profile is applied to every tube in a run, which removes the analyst-to-analyst variation that manual rinsing introduces.

The speed advantage is significant. Copley reports that the DTS 100i offers drug recovery up to ten times quicker than manual practice . In a busy QC lab running multiple batches, that time compounds across a shift. The unit also reduces the physical burden of repeated manual shaking, which is a known source of repetitive strain injury in inhaler testing labs .

For buyers sourcing through OS4U, the configuration questions are whether MDI or DPI tube holders are needed (or both), whether IQ/OQ documentation is required for your quality system, and whether the unit will be integrated into an existing DDU workflow. The Copley Scientific DUSA Shaker page lists the current options.

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Key Benefits

Reproducible recovery without manual variability

The DTS 100i automated DUSA shaker applies the set shake speed and motion profile identically to every collection tube. The recovery condition does not depend on how an analyst shook the tube by hand, which removes a known source of DDU data variability .

Up to ten times faster than manual rinsing

Copley reports that the DTS 100i delivers drug recovery up to ten times quicker than manual practice . For a QC lab processing batches, that speed translates directly into throughput.

Flexible motion for different formulations

Shake only, roll only, or shake and roll are all selectable. Shake speed is adjustable from 20 to 200 RPM, and roller speed is fixed at 11.4 RPM. Different formulations and solvent systems can be matched to the appropriate motion profile .

Capacity for batch processing

Ten MDI or ten DPI collection tubes per run. For a study requiring multiple replicates, the DTS 100i processes a batch rather than one tube at a time .

Reduces repetitive strain injury risk

Automating the repetitive shaking motion reduces the physical burden on analysts who would otherwise perform the procedure manually for every tube in every batch .

Programmable run time up to 100 hours

The run time can be set up to 100 hours, covering extended recovery periods for low-solubility formulations or methods that require longer agitation .

Compact benchtop footprint

The 410 x 626 x 227 mm footprint fits on a standard lab bench without dominating the workspace .

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Solving the Problems That Slow DDU Testing Down

Struggling with inconsistent recovery between analysts? The shake speed and motion profile are set digitally and applied identically to every tube. The recovery condition does not depend on manual technique.

Losing analyst time to manual shaking? The DTS 100i automates the motion and delivers recovery up to ten times faster than manual practice. The analyst is free for other work while the run proceeds .

Worried about analyst strain from repetitive shaking? The unit automates the repetitive motion, reducing the physical burden of DDU testing .

Running both MDI and DPI products? The DTS 100i accepts ten MDI or ten DPI collection tubes, with the appropriate holders .

Needing different agitation for different formulations? Shake only, roll only, and shake-and-roll modes are all available, with adjustable shake speed .

Needing to qualify the instrument under GxP? IQ/OQ documentation is available as a separate option .

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Warranty & Support

We provide a 1-year manufacturer’s warranty covering parts and labor. Technical support, installation assistance, and operational training are also available. Replacement parts and consumables are available throughout the product’s service life.

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