Technical Specifications

The Sample Recovery System SRS 100i is an automated drug recovery system from Copley Scientific, designed to address one of the most operator-dependent steps in inhaler testing. It automates solvent dispensing, dissolution, and sample collection for delivered dose uniformity (DDU) and aerodynamic particle size distribution (APSD) workflows, producing HPLC-ready samples without manual intervention. The system operates with a controlled four-stage workflow: Load, Dispense, Dissolve, and Collect. It is compatible with standard components including DUSA systems, impactors such as the NGI and ACI, induction ports, and preseparators . The specifications below cover the standard unit.

Model/Part Number: SRS 100i (Sample Recovery System)

Dispensing and Agitation

• Dispensing accuracy: ±1%

• Agitation speed: 10–60 RPM (±1 RPM)

• Run time: Up to 24 hours (up to 60,000 revolutions)

• Workflow stages: Load, Dispense, Dissolve, Collect

Compatibility

• DDU workflows: DUSA systems and associated components

• APSD workflows: Next Generation Impactor (NGI), Andersen Cascade Impactor (ACI), induction ports, preseparators

• Software integration: Inhalytix®+ compatible for method and parameter transfer, unified traceable workflows, and downstream HPLC result import

Data Integrity and Compliance

• Regulatory design: 21 CFR Part 11 and GMP

• Electronic records: Built-in functionality supporting data integrity and traceability

• Reproducibility: Standardised solvent delivery, dissolution, and sample handling reduce operator-dependent variation

Connectivity and Physical Specifications

• Connectivity: USB A, USB B, RS-232 (run in digital input)

• Dimensions (W x D x H): 1250 x 605 x 605 mm

Standard Accessories Included:

• SRS 100i Sample Recovery System base unit

• Dedicated holders for test components

• Power cable

• Operating manual

Items Excluded:

• DUSA systems, impactors (NGI, ACI), induction ports, and preseparators (existing laboratory equipment)

• HPLC vials and consumables

• Inhalytix®+ software license (where not already owned)

• IQ/OQ documentation and qualification services

• Installation and training services

Pre-installation Requirement:
Place the system on a rigid, level bench capable of supporting the unit and loaded test components, with clearance for the automated workflow and access to the sample collection area. Connect to a grounded power supply matching the nameplate. Connect the USB and RS-232 interfaces as required for data transfer and Inhalytix®+ integration. Ensure the solvent supply is connected and primed before the first run. Allow the system to reach ambient temperature before first use if stored in a different environment. Confirm the dedicated holders for your test components (DUSA, impactor stages, etc.) are fitted and seated correctly before loading samples.

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Why This System Belongs in an Inhaler Testing Lab

Drug recovery is the step where good aerosol data goes to die. The impactor or DUSA collection is complete, the drug is on the collection surfaces, and then an analyst has to recover it manually with solvent, rinsing, and transfer to a vial. Every hand movement introduces variation: solvent volume delivered, rinsing technique, transfer completeness. The SRS 100i automated drug recovery system for inhaler testing exists to remove that variation. It standardises solvent dispensing, dissolution, and sample collection into a defined four-stage workflow, producing HPLC-ready samples with the same execution across runs, analysts, and sites .

The alignment with established methods is what makes the transition practical. The SRS 100i is designed to closely align with manual recovery approaches, replicating the key steps within a controlled, automated workflow. Laboratories do not need to revalidate their entire recovery method; they transfer the existing method into a more repeatable execution .

The Inhalytix®+ compatibility closes the data loop. Method parameters and operational data transfer into Inhalytix®+, and downstream HPLC results can be imported back to complete the dataset. The recovery record, the analytical result, and the reporting all sit in one traceable platform .

For buyers sourcing through OS4U, the configuration questions are whether the dedicated holders for your specific impactor or DUSA components are included, whether IQ/OQ documentation is required, and whether Inhalytix®+ is already in use in your laboratory. The Copley SRS 100i page lists the full technical specifications and compatibility details.

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Key Benefits

Reproducibility that crosses analysts and sites

The SRS 100i sample recovery system for DDU and APSD workflows controls the variables that manual recovery leaves to technique: solvent volume, dispensing, dissolution action, and sample collection. The result is consistent execution across runs, analysts, and laboratory sites, reducing the variability that drives out-of-specification investigations .

Four-stage workflow with no manual intervention

Load, Dispense, Dissolve, Collect. Test components are placed in dedicated holders, solvent is delivered automatically, controlled agitation supports dissolution, and prepared samples are aspirated into HPLC vials. The analyst does not handle the sample between loading and collection .

HPLC-ready samples without transfer steps

The prepared samples are aspirated directly into HPLC vials. The transfer step that introduces loss and contamination in manual recovery is eliminated, and the samples are ready for immediate analysis .

Compatible with the equipment already on your bench

The SRS 100i works with DUSA systems, NGI, ACI, induction ports, and preseparators. The recovery system fits the existing inhaler testing setup rather than requiring a new collection platform .

Inhalytix®+ integration for traceable data

Method and operational parameters transfer into Inhalytix®+, supporting unified, traceable workflows for APSD measurement. Downstream HPLC results can be imported to complete the dataset. The recovery record and the analytical result connect in one platform .

Designed for regulated environments

21 CFR Part 11 and GMP compliance are built into the system design. Electronic records functionality supports data integrity and traceability, and the standardised workflow provides the controlled, repeatable execution that regulatory review expects .

Extended run capability

Run time up to 24 hours and up to 60,000 revolutions. Batch or overnight processing is supported, so the system can run unattended through a full sample set .

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Solving the Problems That Slow Drug Recovery Down

Getting variable recovery results between analysts? The SRS 100i standardises solvent delivery, dissolution, and sample handling. The execution is the same regardless of who loads the system, removing operator technique from the result .

Losing sample during manual transfer to HPLC vials? The prepared samples are aspirated directly into vials. The transfer step that introduces loss and contamination is automated, and the samples are HPLC-ready without manual handling .

Worried about cross-contamination between samples? The automated workflow with dedicated holders and controlled solvent delivery eliminates the manual handling that risks carryover. The system is designed to prevent cross-contamination .

Needing to fit the recovery system into an existing workflow? The SRS 100i aligns with established manual recovery methods and is compatible with DUSA, NGI, ACI, and associated components. The transition from manual to automated does not require a new collection platform .

Struggling to connect recovery data with analytical results? Inhalytix®+ compatibility transfers method parameters and operational data into a unified platform. HPLC results can be imported to complete the dataset, supporting traceable, defensible records .

Facing regulatory scrutiny of manual recovery steps? The system is designed for 21 CFR Part 11 and GMP environments, with electronic records functionality supporting data integrity. The standardised workflow provides the controlled execution that audit review expects .

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Budgetary Price and Final Price Calculation

Copley Scientific does not publish a budgetary price for the SRS 100i Sample Recovery System on its website, brochures, or distributor listings. The product is quotation-based, which is standard for capital equipment in pharmaceutical testing. No price figure is stated here because a published figure does not exist.

To obtain the budgetary price and complete the requested calculation:

• Contact Copley Scientific directly (sales@copleyscientific.co.uk) or their regional distributor for Bangladesh (Apex Chromatography) .

• Request a budgetary quotation for the Sample Recovery System SRS 100i.

• Once the budgetary price is received, multiply it by 300 to obtain the final price.

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Warranty & Support

We provide a 1-year manufacturer’s warranty covering parts and labor. Technical support, installation assistance, and operational training are also available. Replacement parts and consumables are available throughout the product’s service life.

Request a Quotation or Technical Datasheet

Contact us for more information, customized configurations, and solutions tailored to your specific requirements.