Technical Specifications

The DISi Series is a line of tablet dissolution testers from Copley Scientific, available in two configurations: the compact 6-station DIS 600i and the 8-station DIS 800i. Both models are designed for pharmaceutical R&D and quality control laboratories, with precision-ground shafts that accept any basket, paddle, or rotating cylinder described in the Ph. Eur., USP, and associated pharmacopoeias. The systems feature an independent digital heater/circulator to minimise vibration, a PT100 temperature probe with electronic calibration, and an intuitive touchscreen interface. The specifications below cover the series platform, with model-specific differences noted.

Model/Part Number: DIS 600i (catalog number 1336); DIS 800i (catalog number 1338)

Configuration and Compliance

• Number of stirred vessels: 6 (DIS 600i); 8 (DIS 800i)

• Pharmacopoeial compliance: Ph. Eur. 2.9.3 and 2.9.4; USP <711> and <724>

• Test methods supported: Ph. Eur. and USP Apparatus 1, 2, 5, and 6

• Shaft compatibility: precision-ground shafts accept any Ph. Eur./USP basket, paddle, or rotating cylinder

Temperature Control

• Heater type: low-vibration independent external digital heater/circulator

• Temperature probe: PT100, monitors bath and vessel temperature

• Calibration: single-point electronic calibration, passcode-protected

• Calibration data: latest information stored and available for export/print

Vessel and Lid Features

• Vessel centring: Easy-Centre system for precise positioning

• Vessel identification: all vessels serial-numbered as standard

• Lids: easy-clean Viton® membrane-sealed low-evaporation lids included as standard

• Bath: easily removable, leak-proof with drain tap

• Fill indicator: maximum fill line indicator

Control and Data

• User interface: intuitive touchscreen with icon-based menu

• Sampling alerts: programmable timepoint warnings and alerts

• Data output: RS-232, USB A, USB B

• Automation: option to automate and remotely control DISi Series systems

Physical Specifications

• Unit dimensions (W x D x H): 728 x 495 x 689 mm

• Heater dimensions (W x D x H): 260 x 330 x 150 mm

Standard Accessories Included:

• DISi Series dissolution tester base unit (6 or 8 stations)

• Independent digital heater/circulator

• PT100 temperature probe

• Easy-clean Viton® membrane-sealed lids

• Serial-numbered vessels

• Certificate of compliance to Ph. Eur./USP

• Power cable

• Operating manual

Items Excluded:

• Baskets, paddles, and rotating cylinders (ordered separately per method)

• IQ/OQ/PQ documentation packages and toolkits (available separately)

• Calibration and qualification tools

• Automation/remote control accessories

• Installation and training services

Pre-installation Requirement:
Place the dissolution tester on a rigid, level bench capable of supporting the unit, heater, and filled vessels, with clearance for the touchscreen and access to all stations. Connect the heater/circulator to a grounded power supply matching the nameplate. Fill the bath and vessels with dissolution medium prepared according to the method, and allow temperature equilibration before testing. Confirm the PT100 probe is connected and the temperature calibration is current. Verify the vessel centring and serial numbers match the method documentation before the first run.

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Why This Tester Belongs in a Pharmaceutical Dissolution Lab

Dissolution testing is one of the most regulated and most frequently run tests in a pharmaceutical quality control laboratory. The result determines batch release, and the method must be defensible to an auditor. The DISi Series dissolution tester for tablet testing was built around that reality. Both the DIS 600i and DIS 800i carry a certificate of compliance to Ph. Eur. and USP as standard, and the precision-ground shafts accept every apparatus described in the pharmacopoeias without adjustment .

The temperature control architecture matters for method transfer. The independent digital heater/circulator is external to the unit, which minimises the vibration that can affect dissolution hydrodynamics. The PT100 probe monitors both bath and vessel temperature, and the single-point electronic calibration is passcode-protected with the calibration data stored for export or print. When a method specifies 37 °C ± 0.5 °C, the system documents what the vessels actually reached.

The sampling alerts are a practical addition that addresses a common failure mode. Timepoints are entered, the test begins, and the system warns before and at each required sampling time. Missing a timepoint invalidates the test; the alert prevents that from happening.

For buyers sourcing through OS4U, the configuration questions are the 6-station or 8-station format, the baskets and paddles needed for your methods, and whether IQ/OQ/PQ documentation is required for your regulatory environment. The Copley DISi Series page lists the full specifications and accessories.

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Key Benefits

Pharmacopoeial compliance with documentation

The DISi Series dissolution testing equipment carries a certificate of compliance to Ph. Eur. 2.9.3/2.9.4 and USP <711>/<724> as standard. The shafts accept Apparatus 1, 2, 5, and 6 without modification, and the compliance documentation supports method validation and audit review .

Compact 6-station or spacious 8-station format

The DIS 600i is one of the most compact dissolution testers available, suited to laboratories where bench space is limited. The DIS 800i adds two stations and maximises visibility and access to the critical sampling area above the bath. The choice depends on throughput requirements and available space.

Low-vibration temperature control

The independent external digital heater/circulator maintains constant temperature while minimising the vibration that can affect dissolution hydrodynamics. The PT100 probe monitors bath and vessel temperature, and calibration data is stored electronically.

Easy-Centre vessel positioning

The Easy-Centre system ensures precise vessel positioning every time. Vessels lock into place and will not become loose or float, even when empty. All vessels are serial-numbered as standard, supporting traceability.

Sampling alerts that prevent missed timepoints

Timepoints are programmed into the system. The tester warns before each sample time and alerts at the required time. Missing a timepoint is a common source of invalidated tests; the alert system addresses it directly.

Method change in seconds

Screw-in baskets and paddles allow method changes without tools. The precision-ground shafts accept any pharmacopoeial apparatus, and the screw-in design means the change from Apparatus 1 to Apparatus 2 takes seconds rather than minutes.

IQ/OQ/PQ documentation available

Comprehensive IQ/OQ/PQ documentation packages and toolkits are available for regulated laboratories. The qualification documentation supports installation, operational, and performance qualification in the laboratory environment.

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Solving the Problems That Slow Dissolution Testing Down

Struggling with bench space for an 8-station tester? The DIS 600i is one of the most compact dissolution testers available, with 6 stations. The DIS 800i offers 8 stations when throughput demands it.

Worried about vibration affecting dissolution results? The independent external heater/circulator minimises vibration. Temperature is controlled without introducing the mechanical disturbance that affects hydrodynamics.

Getting vessel positioning wrong between runs? The Easy-Centre system locks vessels into precise position every time. The vessels will not float or become loose, even when empty.

Missing sampling timepoints during a run? The system alerts before and at each programmed timepoint. The analyst is warned, and the test is not invalidated by a missed sample.

Needing audit-ready temperature data? The PT100 probe monitors bath and vessel temperature, and calibration data is stored and available for export or print. The record documents the conditions the method required.

Needing qualification documentation for a regulated lab? IQ/OQ/PQ documentation packages and toolkits are available. The system can be qualified for use in GMP environments.

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Budgetary Price and Final Price Calculation

Copley Scientific does not publish a budgetary price for the DISi Series on its official website. A third-party distributor listing shows the DIS 600i at 48,250.00 Lei (Romanian Leu), which is approximately $10,615 USD at current exchange rates . This is a distributor's listed price, not a direct quote, and may not reflect the configuration, accessories, or documentation you require.

Using this estimated figure for calculation purposes:
Estimated Budgetary Price (DIS 600i): ~$10,615 USD**
**Requested Multiplier: × 300**
**Final Calculated Price: ~$3,184,500 USD

This figure is an estimate only. For a purchase of this scale, you must obtain a formal budgetary quotation directly from Copley Scientific (sales@copleyscientific.co.uk) or their regional distributor for Bangladesh (Apex Chromatography). The actual price will depend on the model (DIS 600i or DIS 800i), the accessories, and the qualification documentation required.

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Warranty & Support

We provide a 1-year manufacturer’s warranty covering parts and labor. Technical support, installation assistance, and operational training are also available. Replacement parts and consumables are available throughout the product’s service life.

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